Figure 1.
The cyclooxygenase (COX)-1 and -2 pathway. Prostaglandins (PG) are formed by specific isomerases from the COX product PGH2. They act through G protein transmembrane receptors.
Abbreviations: IP, prostacyclin receptor; TP, thromboxane receptor; DP, PGD2 receptor, EP, PGE2 receptor, FP, PGF2α receptor.