Figure 6.
Sub-clonal genetic structure in a patient withETV6-RUNX1–positive acute lymphoblastic leukemia (ALL).
Arrow, ETV6-RUNX1 fusion (F). RUNX1, orange. ETV6, green. PAX5, magenta.
Circles (percentage) = subclones with distinctive genotypes (gene copy number variations) and their relative proportions in the total ALL cell population.