Figure 7.
Sub-clonal genetic structure in patient withETV6-RUNX1–positive acute lymphoblastic leukemia (ALL).
Dashed arrow = possible derivation.
% proportion of fusion gene–positive cells in leukemic population with particular genotype.
0, 1, 2, 3 numbers against gene name: copy number identified by FISH.
F, ETV6-RUNX1 fusion.
1/2/3 RUNX1, copy number of chromosome 21 region including RUNX1 gene.