Overall survival of transfusion-dependent patients with myelodysplastic syndrome (MDS) according to ferritin level. The survival effect is mainly seen in lower risk patients, RA, RARS and 5q-, shown on the left as compared with higher risk, RCMD and RCMD-RS, shown on the right. Adapted from Malcovati L, et al. Haematologica. 2006;91:1588–90, with permission from the Ferrata Storti Foundation, Pavia, Italy.