Ten-year relative survival curves of patients with ALL by major age groups. Period estimates for 1980–1984 (solid curves) and 2000–2004 (dashed curves).
 Reprinted with permission from Pulte D, Gondos A, Brenner H. Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century. Blood. 2009;113:1408–1411.²⁵