Prevalences of elevated transferrin saturation (TfS) and serum ferritin (SF) in C282Y homozygotes in the HEIRS Study.
 Vertical bars represent the proportion of HFE C282Y homozygotes whose TfS and SF values exceeded study thresholds: TfS > 50% and SF > 300 μg/L for men (N = 89); TfS > 45% and SF > 200 μg/L for women (N = 138). Adapted with permission from Adams PC et al. N Engl J Med. 2005;352:1769–1778.²⁹