Age-specific incidence of acute chest syndrome episodes (panel A) and pain episodes (panel B) in the infant sickle cell anemia cohort from the Cooperative Study of Sickle Cell Disease.
 Reprinted with permission from Boyd JH, Macklin EA, Strunk RC, DeBaun MR. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood. 2006;108:2923–2927.¹¹