Figure 2.
Levels of canine Factor IX (cFIX) in mice transduced with a retroviral vector. (A) Neonatal mice injected intravenously with a single dose of 1 × 1010 TU/kg at 2 to 3 days of age. The normal range of Factor IX levels is indicated by the gray bar. (B) Levels of cFIX in adult mice infused intravenously with the same vector following infusion with hepatocyte growth factor. (C) Levels of cFIX in adult mice infused intravenously with the same vector but without preceding hepatocyte growth factor infusion. Adapted with permission from Xu et al.7
