Alter Figure 1B.
Telomere maintenance pathway. Telomeres contain hexanucleotide repeats (TTAGGG)n and associated proteins involved in the addition of these base pairs during mitosis. The major components of the telomerase pathway are the RNA template and the telomerase enzyme, but multiple proteins are involved, only some of which are shown in the figure.
Reprinted by permission from Macmillan Publishers Ltd:
Nature Reviews Immunology. 2002;2:699–706
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