Reduced homing and short term reconstitution in Arhgap21^+/- recipients. Bone marrow cells from GFP⁺ mice were injected into wild-type and Arhgap21^+/- sublethally irradiated mice. 19 hours after the transplant, a decreased homing was observed to both bone marrow (a) and spleen (b) together with an increase of retained peripheral blood (c) Lin^-GFP⁺ cells. In serial bone marrow transplantation, Arhgap21^+/- presented reduced bone marrow LSK GFP⁺ cells 8 weeks (d) and peripheral blood GFP⁺ cells 12 weeks (e) after primary transplantation, though not 16 weeks after primary (f) and 16 weeks after secondary (g) transplantations. The result is expressed by means ±SD of 2 independent experiments.