Clinical and laboratory parameters in our study subjects: A) Asian Indian (East Indian) female (proband), compound heterozygous for Hb Monroe and Hb E; B) Asian Indian (East Indian) male (proband’s brother), heterozygous for Hb Monroe; C) African American female #1, heterozygous for Hb Monroe; D) African American female #2, heterozygous for Hb Monroe.