Representative images of xenografts. On day 1, 5 × 106 viable cells of each tumor were injected i.p. Necropsy was performed on day 14 (except row 5, which was performed at 1 month). Representative images from 6 of 20 tumors are shown. Staining was by hematoxylin and eosin (H&E) unless otherwise stated. Row 1: tumor B is a diffuse large B-cell lymphoma. Column 1: xenograft in omentum. Column 2: xenograft (full extent of omental implant). Column 3: CD20 in omentum. Column 4: CD3 in omentum. Row 2: tumor C is a mantle cell lymphoma. Column 1: xenograft in omentum. Column 2: splenic section showing xenograft stained for BCL1 in a white pulp distribution. Column 3: CD20 in spleen. Column 4: CD3 in spleen. Row 3: tumor E is a follicular lymphoma, grade one. Column 1: xenograft in omentum. Column 2: xenograft (representative cross-section of the omental implant with adjacent pancreas). Column 3: CD20 in omentum. Column 4: CD3 in omentum. Row 4: tumor G is a diffuse large B-cell lymphoma. Column 1: xenograft in omentum. Column 2: representative cross-section of the omental implant. Column 3: CD20 in omentum. Column 4: CD3 in omentum. Row 5: tumor G is same tumor as prior row, showing involvement of the lung at 1 month. Columns 1 and 2: xenograft surrounding airway. Column 3: CD20 in lung. Column 4: CD3 in lung. Row 6: tumor J is a follicular lymphoma, grade 2. Column 1: xenograft in omentum. Column 2: white pulp pattern of splenic involvement. Column 3: CD20 in spleen. Column 4: CD3 in spleen. Row 7: tumor L is a follicular lymphoma, grade one. Column 1: xenograft in the omentum (representative cross-section of full omental tissue). Column 2: xenograft in omentum. Column 3: CD20 in omentum. Column 4: CD3 in omentum.
