Graphic working model of the project. To create a database of blood group gene alleles, we imported data from the 1000G project, reference data sources, and LRG into a SQL database. Data were curated carefully with several automated and manual validating procedures. This process also discovered previously undetected errors in the reference data. A matching procedure integrated the data sources, allowing for a searchable interface to the database. The database is available via a Web interface, Erythrogene. dbRBC, Blood Group Antigen Mutation Database; GRCh37, Genome Reference Consortium human genome build 37; ISBT, International Society of Blood Transfusion; LRG, Locus Reference Genomic.