HTS of gDNA from Ghanaian BL tumors identifies the repertoire of Ig rearrangements in tumor cells. (A-B) Cumulative frequency plots of all unique IGH (A) or IGK/IGL (B) sequences identified by HTS of gDNA from the Ghanaian BL cohort. Each segment in the bar plots represents a unique nucleotide sequence, and the color indicates the type of Ig rearrangement. Black lines separate the unique sequences, so polyclonal regions appear black in the figure. *Indicates that the tumor sample was EBV-negative; †indicates that the repertoire was classified as polyclonal.