Good- and poor-risk genotypes were identified for the ASXL1 rs4911231 and BIM rs686952 variants. Univariate analysis of the achievement of MR^4.5 as stratified by (A) the ASXL1 rs4911231 and (B) the BIM rs686952 variant genotype identified good- and poor-risk genotypes which were strongly associated with MR^4.5.