Regional plot of age-specific (<20, 20-40, >40 years) associations with B-ALL in IKZF1. Regional plot showing age-stratified association with B-ALL within IKZF1. The x-axis is the position on the chromosome (Mb), and y-axis is the −log₁₀P value. The circles (older adults), diamonds (young adults) and squares (pediatric) show the P value for the SNP association with risk of B-ALL, rs11980379. Filled colors indicated the LD with the most significant SNP shown in purple. Red indicates a high degree of LD whereas blue indicates lower r². This plot shows a significant association in pediatrics, but no evidence of association with B-ALL in young adults and older adults.