Regional plot of sex-specific associations with B-ALL in IKZF1. Regional plot of sex-specific associations with B-ALL in the IKZF1 region. The x-axis is the position on the chromosome (Mb), and y-axis is the −log₁₀P value. The squares (male) and circles (female) show the P value for the SNP association with risk of B-ALL. Filled colors indicate the LD with the most significant SNP shown in purple. Red indicates a high degree of LD whereas blue indicates lower r².