Figure 7.
Flagellin-induced MPP3 cells significantly increase mouse survival after bone marrow transplantation. Five thousand MPP3 cells were FACS-sorted from whole bone marrow cells from flagellin-treated mice and transferred to irradiated mice along with 1 × 105 whole bone marrow cells from the same species. In parallel, additional group of mice were irradiated and given whole bone marrow cells only. After bone marrow transplantation, mice were housed under sterile conditions, and survival was observed for 30 days. Both donor and recipients were C57BL/6 mice.