CD38 antibody-mediated reduction of NK cells in in vitro ADCC/CDC assays. Bars show percent change of NK cells in the lymphocyte (CD45⁺) population, averaged from 3 replicates from 3 PBMC donors. Error bars represent standard error. Samples were incubated for 3 days and then assessed by flow cytometry. Test sample values were normalized to no complement, no antibody controls. DARA, daratumumab; ISA, biosimilar SAR650984 antibody; Iso, isotype control; MOR, biosimilar MOR202 antibody.