Figure 3.
Transcriptional signature of naive cord blood CD4+ T cells. (A) Venn diagram of differentially expressed genes in 3 microarray experiments comparing the naive CD4+ T cells from normal donor cord blood and peripheral blood. Sixty genes overlapped in the 3 experiments. (B) Sixty genes that represent the signature of naive cord blood CD4+ T cells. (C) Scatterplot of pairwise global gene expression comparison of naive cord blood CD4+ T cells and naive peripheral blood CD4+ T cells. Gene expression values are plotted on a log scale. Genes that were differentially expressed between groups (determined using P < .05 and fold-change ≥2) are indicated in red and blue. Specific genes that were differentially expressed are highlighted with arrows.