Hepatomegaly and liver damage. (A) Liver weight is presented as a percentage of body weight. (B) Serum levels of aspartate transaminase (ASAT), alanine transaminase (ALAT), and lactate dehydrogenase (LDH). Data are presented as the mean ± standard error of the mean. P values were calculated using an unpaired Student t test. (C) Hematoxylin and eosin staining of liver sections at day 14 postinfection. Inflammatory infiltrates are depicted with arrows (upper panel: 10× objective; lower panel: 25× objective). Representative sections are shown. *P < .05; **P < .01; ***P < .001.