Figure 1.
Clinical and morphologic response to fingolimod and steroids in a patient with CNS GVHD. *MRI images are T2-FLAIR weighted; arrowheads indicate main periventricular lesions, which gradually disappeared on treatment. †Scores were not evaluated at the time of the first episode of CNS GVHD. Any MMSE score ≥24 points (out of 30) indicates normal cognition. Any FAB score ≥16 points (out of 18 points) indicates normal executive functions. T0, time of the first episode of CNS GVHD (10 months after allo-HCT).