Figure 1.
Figure 1. Structure and in vitro activity of GSK3277329. (A) Chemical structure of GSK3277329. (B-C) TLR2 agonists stimulate G-CSF release in a concentration-dependent manner in PMA-differentiated human THP-1 cells (n = 2 replicates) (B) and HUVECs (GSK329 n = 6 replicates, PAM2CSK4 n = 2 replicates) (C). Graphs show mean ± standard error of the mean (SEM). Error bars are not shown if the error is smaller than the symbol size.

Structure and in vitro activity of GSK3277329. (A) Chemical structure of GSK3277329. (B-C) TLR2 agonists stimulate G-CSF release in a concentration-dependent manner in PMA-differentiated human THP-1 cells (n = 2 replicates) (B) and HUVECs (GSK329 n = 6 replicates, PAM2CSK4 n = 2 replicates) (C). Graphs show mean ± standard error of the mean (SEM). Error bars are not shown if the error is smaller than the symbol size.

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