The effect of a TLR2 agonist or G-CSF on IL-6 or G-CSF levels in cyclophosphamide-treated M fascicularis. (A) Circulating G-CSF levels in M fascicularis (n = 3 per group) after vehicle, cyclophosphamide (CYP), or CYP plus GSK3277329 (3 mg/kg) or CYP plus G-CSF (10 µg/kg) treatment. (B) Circulating IL-6 levels after vehicle, CYP, or CYP plus GSK3277329 (3 mg/kg) or CYP plus G-CSF (10 µg/kg) treatment. Samples were taken at the indicated times after the first or 14th dose. Mean ± SEM values are plotted. No error bars are shown if the error is smaller than the height of the symbol. Significant differences against the vehicle and CYP groups at each time point using 2-way ANOVA with Tukey’s post hoc test are noted by asterisks (**P < .0001, *P < .005).