Neutrophil counts in vehicle-treated animals or animals treated with 2 doses of cyclophosphamide. Cyclophosphamide (CYP)–treated animals received vehicle or 1, 3, or 7 daily doses of GSK3277329 (15 mg/kg) 2 days after the last cyclophosphamide dose. Neutrophil numbers were counted 7 days after the first dose. Bars represent mean ± SEM. *P < .05 vs vehicle by ANOVA and Dunnett’s multiple comparison post hoc test (n = 3 per group).