ACA-dependent incidence, lineage distribution, and risk ratio of blastic transformation. (A) Incidence and lineage distribution of BP in patients with different types of ACAs acquired before or at blastic transformation and in patients without ACAs. The incidence of mixed-phenotype BP (MPBP) was 0.6% overall and 0.2% in the patients with no ACAs. (B) Risk ratio associated with different types of ACAs.