Figure 4.
B1 and B2 B-cell repertoire in 3′RR-deficient and wt mice. B1 and B2 B cells of wt and 3′RR-deficient mice were cell sorted from pooled cells of 12 and 13 mice, respectively. 2.1 × 106 and 2.8 × 106 B1 B cells were sorted for wt and 3′RR-deficient mice, respectively. 0.8 × 106 and 1.3 × 106 B2 B cells were sorted for wt and 3′RR-deficient mice, respectively. (A-B) V usage frequency in (A) B2 and (B) B1 B cells of 3′RR and wt mice. (C) Gini index for B1 and B2 B cells of 3′RR and wt mice. The Gini index measures the inequality of clone size distribution and is bound between zero and 1. An index of zero represents a clone set of equally distributed clones, all having the same size, whereas a Gini index of 1 would point to a set including only 1 clone.