Blood and BM investigations and clinical course (2006-2015). Progress of hemoglobin (Hb) and platelet count (top). Progress of white blood cell count (WBC), neutrophils (N), monocytes (Mo), and blasts (B) in the blood (middle). Table listing diagnostic details, absolute monocyte counts, and clinical events (bottom). LRTI, lower respiratory tract infection; MF, myelofibrosis.