Philipps score and menorrhagia bleeding scores in women with low VWF. (A) Bar chart of the number of women with positive responses to the 4 domains included in the Philipps tool. (B) Comparison of the ISTH BAT and Condensed MCMDM-1 VWD menorrhagia-domain score in women with low VWF using identical clinical information (median 3 vs 2, P < .0001, median and interquartile range [IQR], indicated for Condensed MCMDM-1 VWD; for the ISTH BAT both the median and IQR are equal to 3). (C-D) Bar chart of menorrhagia-domain bleeding scores by lowest recorded plasma VWF levels. When examined by lowest recorded plasma VWF levels, 84% of those female enrollees with lowest levels (30-39 IU/dL) had ISTH BAT menorrhagia-domain scores ≥3 in comparison with 67% of patients with lowest plasma VWF level (40-50 IU/dL) (C). A similar pattern was seen using the Condensed MCMDM-1 VWD score (D).