Stratification of the whole cohort of patients (n = 263) according to the risk of developing acute GVHD. Risk was calculated using the proposed predictive model including clinical variables (upper panels), genetic variables (middle panels), or both clinical and genetic variables (lower panels). Cumulative incidence curves are shown for the development of grade 2 to 4 aGVHD (left panels) and grade 3 to 4 aGVHD (right panels). The cutoff used was 0.28 for grade 2 to 4 aGVHD and 0.11 for grade 3 to 4 aGVHD.