Figure 3.
Immunohistochemical analysis of thrombus inflammation and angiogenesis. Thrombosed IVC segments of adult and aged End.p53-WT or End.p53-KO mice were examined 21 days after surgery. (A) Quantitative analysis of the Mac2-immunopositive area per thrombus area. (B) Representative images. Scale bars represent 200 µm. (C) Quantitative analysis of the CD3-immunopositive area per thrombus area. (D) Representative images. Scale bars represent 200 µm. (E) Quantitative analysis of the CD31-immunopositive area per thrombus area. *P < .05. (F) Representative images. Scale bars represent 50 µm. Individual values and the mean ± SEM (A) or the median ± interquartile range (C,E) are shown.