Figure 2.
Figure 2. Ploidy of in vitro–grown megakaryocytes. (A) Example of ploidy distribution of day 12 CD42bHigh megakaryocytes after the indicated treatments. (B) Same as panel A, but showing mean ploidy ± 1 SEM. (C) Same as in panel B but mean percentage ± 1 SEM of megakaryocytes that were ≥8N. In both panels B and C, N = ≥5 independent experiments. P values were determined using 1-way ANOVA in comparison with the control. AZD, exposed to the aurora kinase inhibitor AZD1152; Ctl, control exposed to DMSO only; RI, exposed to the ROCK inhibitor Y27632; SU, exposed to the Src inhibitor SU6656.

Ploidy of in vitro–grown megakaryocytes. (A) Example of ploidy distribution of day 12 CD42bHigh megakaryocytes after the indicated treatments. (B) Same as panel A, but showing mean ploidy ± 1 SEM. (C) Same as in panel B but mean percentage ± 1 SEM of megakaryocytes that were ≥8N. In both panels B and C, N = ≥5 independent experiments. P values were determined using 1-way ANOVA in comparison with the control. AZD, exposed to the aurora kinase inhibitor AZD1152; Ctl, control exposed to DMSO only; RI, exposed to the ROCK inhibitor Y27632; SU, exposed to the Src inhibitor SU6656.

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