Figure 1.
Figure 1. Comparison of Cycle 1 and Cycle 2 apheresis products and clinical outcome data in MM patients. In Panels A-C, paired Cycle 1 and Cycle 2 values for each patient are connected by a line. Open circles represent A) Total rearranged Ig molecules (an approximation of total B-cells) as a fraction of total cells, B) Number of myeloma molecules per million PBMCs, and C) Myeloma clonotype frequency relative to total Ig rearrangements for each patient in the Cycle 1 and Cycle 2 apheresis products. D) Kaplan-Meier analysis of progression-free survival for 7 MRD negative (<10-5) and 12 MRD positive (>10-5) patients.

Comparison of Cycle 1 and Cycle 2 apheresis products and clinical outcome data in MM patients. In Panels A-C, paired Cycle 1 and Cycle 2 values for each patient are connected by a line. Open circles represent A) Total rearranged Ig molecules (an approximation of total B-cells) as a fraction of total cells, B) Number of myeloma molecules per million PBMCs, and C) Myeloma clonotype frequency relative to total Ig rearrangements for each patient in the Cycle 1 and Cycle 2 apheresis products. D) Kaplan-Meier analysis of progression-free survival for 7 MRD negative (<10-5) and 12 MRD positive (>10-5) patients.

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