LPS-induced elevations of MPO levels was noted in the lungs of P2Y12null mice. MPO analysis was performed in lung samples of untreated and LPS treated WT (black) and KO mice (white) before and after clopidogrel exposure. Values are expressed as fluorescence mean ± SEM (*p < 0.01; **p < 0.05; KO model versus WT, treated versus untreated; n=3).