Figure 2.
Figure 2. Western blot analysis demonstrates hyperactive Ras-Erk signaling in E14.5 fetal liver and E9.5 yolk sac progenitors from PTPN11D61Y/+; VavCre+ embryos. Cultured progenitors were starved overnight and stimulated with GM-CSF for 60min prior to protein extraction. p, phosphorylated protein; t, total protein; WT, wild type.

Western blot analysis demonstrates hyperactive Ras-Erk signaling in E14.5 fetal liver and E9.5 yolk sac progenitors from PTPN11D61Y/+; VavCre+ embryos. Cultured progenitors were starved overnight and stimulated with GM-CSF for 60min prior to protein extraction. p, phosphorylated protein; t, total protein; WT, wild type.

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