Comparison of thrombin generation induced by two different microparticle species: endothelial microparticles (EMP; black columns) versus microparticles derived from a cancer cell line (A431-MP; gray columns). Thrombin generation was measured in plasmas deficient in coagulation factors (F) VII, VIII, IX, X, XI, or XII. Values are expressed as percentage of thrombin amounts measured in normal plasma (*P < 0.05, **P < 0.01, and ***P < 0.001).