sB1^−/− PMN death mediated by CG does not require caspase activity. Survival of isolated BM PMNs in the presence of 50µM pan-caspase inhibitor Q-VD-OPh was measured by flow cytometry (supplemental Figure 1) at indicated time points for (A) WT and sB1^−/− PMNs (N = 3) and (B) CG^−/− and CG^−/−.sB1^−/− PMNs (N = 2). Data are shown as mean ± SD and was analyzed by 2-way ANOVA followed by the Bonferroni posttest (***P < .001).