Rapid effect of TDZD-8 compared with PTL on CD34+38− AML cell viability (top panel). Loss of membrane integrity as measured by MBBr with both TDZD-8 and DMAPT (bottom left; shaded histograms) and YoPro-1 (bottom right; TDZD-8). See the complete figures in the articles beginning on pages 4427 and 4436.