Decreased amidolytic activity in arteries of mice treated with dermatan sulfate. Dermatan sulfate (20 μg/g) or an equal volume of normal saline was administered intravenously to wild-type mice 5 minutes after carotid injury. The injured arterial segments were harvested 30 minutes later and assayed for thrombin activity with tosyl-Gly-Pro-Arg-p-nitroanilide. Mean values are indicated. Error bars equal 1 SD.