Photographs of the feet and computed tomographs of the chest of a patient treated with IL-12 and liposomal doxorubicin. Images in panels A and C were taken at baseline; those in panels B and D were taken at 22 months of treatment, the time of complete response. This patient was docu-mented to have a partial response at 4 weeks. Panels A and B were taken by NIH Patient Photographic Services using Nikon Digital SLR cameras (D1 and D1X respectively). Computed tomography scans were acquired from the NIH Clinical Center Diagnostic Radiology Department using the Kodak Carestream PACS web-based program. Images were imported into Adobe Photoshop v7 (Adobe Systems, San Jose, CA) for cropping and labelling. The images were then converted into a single Microsoft JPEG using MS Word 2003 (Microsoft, Seattle, WA) for importing into the manuscript as a single picture.