Functional properties of anti-C2 MAb groups. (A) Relationship between MAb group, fVIII inhibitor titer (●), and IC₅₀⁻¹ values for inhibition of binding of fVIII to phospholipid (○). (B) The inhibitor titers of MAbs with demonstrable inhibition of binding of fVIII to phospholipid (○) or VWF (●) (Table 1) are plotted versus IC₅₀⁻¹ for inhibition of binding.