Figure 2
![Figure 2. AICD in lymphocytes from Fas-defective patients and healthy controls. TSST-1 AICD (B) was compared with Fas sensitivity (A) of T cells from 6 ALPS-I patients (P1 to P6), from 2 healthy mutation positive relatives (fP1 and fP6), and from eight age-related control donors. Experiments were performed as described in Figure 1 using TSST-1/TSST-1 activation/restimulation. The shaded gray zones indicate means of apoptosis induced by Fas or TSST-1 AICD in control-cells (n = 21; in panel A, mean = 89% ± 2% [SEM]; in panel B, mean = 68% ± 2%).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/110/13/10.1182_blood-2007-05-088286/3/zh80240710300002.jpeg?Expires=1735588062&Signature=iTD2CRdm-EjCycAArngh4tCkKW2ynFbX1KpvEqJEwrLxfFe1x8zsHgWz0E96EUujzNwaA~cgn0kHaxebK6c5karc8mIICZI64ZfO2FTrM5l2D7x63b~xRMKdIQHJYPgg1x7-M-ZSdVonLr6oNHIldGU3hh0sFvhzU2Gep3frbTynlrDym6EC4Gx97iQ~~4GEYcjqaWnYTUI5yDiJtF3ReFxU5EM7a3kmWxMt-gTK03KJSnk802zYAMiAR6ioQa5gSa5b7ZjcivI6ezPJt2-CXaD6PEdvwoO5qaH2nBC0pVxU7puR1hXxB93LQk4wEhyLG4tgC4ZjOrjBlKB-D1yH1Q__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
AICD in lymphocytes from Fas-defective patients and healthy controls. TSST-1 AICD (B) was compared with Fas sensitivity (A) of T cells from 6 ALPS-I patients (P1 to P6), from 2 healthy mutation positive relatives (fP1 and fP6), and from eight age-related control donors. Experiments were performed as described in Figure 1 using TSST-1/TSST-1 activation/restimulation. The shaded gray zones indicate means of apoptosis induced by Fas or TSST-1 AICD in control-cells (n = 21; in panel A, mean = 89% ± 2% [SEM]; in panel B, mean = 68% ± 2%).
