Figure 2
![Figure 2. CD8+ T-cell responses to PR1 and WT1 vaccination by intracellular IFN-γ assay. (A-C) Longitudinal data on IFN-γ production by CD8+ T cells in PBMC samples from patient 8, cultured for 6 hours with PR1 (A), with WT1 (B), or without peptide (negative control [C]) are presented. Results are expressed as percentages of total CD8+ T cells. (D,E) Frequencies of PR1- and WT1-specific CD8+ T cells by tetramer analysis and IFN-γ production were compared and found to be highly correlated; P < .001.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/111/1/10.1182_blood-2007-08-108241/3/zh80020811290002.jpeg?Expires=1736058719&Signature=Xoy1sPc0Hyh4aN980Vls9az4tVASapTj62bm~aeeFT0AWiEJPp60DuYUGTad3Do5WKsg86LJSMYWX7zOIUBDoIvMnJQ8RdMw3kpLIZM7qDK~LKqjXmiuniLdKexq6Kr3vJLAlQshmssnux78yiYYUjAjwg74lMDByUNzQ1pu3JKbCqwJN9KtDimZe~xsOxLD2sIq2dB7bT6-qxw8ug3QuxvApHHa4zT7G025ITCHYozlK8TTdvHT8yT9xU7-2fEehMlGrcMLnFE5hv8jiTktCnYBY4aCf1egEWSUPAp9buKzth9tNy0HXIKvTXIwKzvynIeTuFZGxuYFyWpaYKEcXQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CD8+ T-cell responses to PR1 and WT1 vaccination by intracellular IFN-γ assay. (A-C) Longitudinal data on IFN-γ production by CD8+ T cells in PBMC samples from patient 8, cultured for 6 hours with PR1 (A), with WT1 (B), or without peptide (negative control [C]) are presented. Results are expressed as percentages of total CD8+ T cells. (D,E) Frequencies of PR1- and WT1-specific CD8+ T cells by tetramer analysis and IFN-γ production were compared and found to be highly correlated; P < .001.
