PR1- and WT1-specific CD8⁺ T-cell responses in peripheral blood in relation to disease response as measured by WT1/ABL and BCR-ABL/ABL gene expression. Results in 8 individual patients are shown. Weeks after vaccination are shown on the x-axis. PR1/HLA-A*0201⁺ (black square and connecting line) and WT1/HLA-A*0201⁺ (dark blue diamonds and connecting line) CD8⁺ T cells are expressed as absolute numbers per milliliter of peripheral blood (left y-axis); the shaded area represents absolute numbers of CMVpp65₄₉₅/HLA-A*0201⁺ CD8⁺ T cells. The absolute lymphocyte count (gray triangle and connecting line) is expressed as absolute number per liter of peripheral blood (left y-axis); WT1 and BCR-ABL gene expression in peripheral blood is expressed as the ratio of WT1/ABL (red circles and connecting line) and BCR-ABL/ABL (red circles and dashed connecting line) (right y-axis).