Figure 1
Chromium 51 studies showing that primaquine sensitivity was due to an intrinsic defect of the red blood cell. (A) Red cells from a primaquine-sensitive volunteer were labeled with chromium 51 and transfused into normal recipients. Three of these recipients were given 30 mg primaquine daily as shown by the bars. (B) Red cells from a primaquine-nonsensitive volunteer were labeled with chromium 51 and transfused into a normal and one primaquine-sensitive volunteer (D.J.). Two of the subjects were given primaquine, including D.J., who was primaquine sensitive. The fall of the hematocrit of D.J. is shown in the lower panel B. (Reprinted from Dern et al67 with permission from Elsevier.)
