T_reg cells migrate in response to CSF supernatants obtained from patients with NM. CIs of T_reg cells from a healthy donor toward CSF supernatants of patients with NM and control diseases as determined by transwell migration assays. Original input PBMCs and migrated cells were stained with CD4/CD25 mAbs and gated on CD4⁺ cells. CI was calculated by dividing percentages of T_reg cells in CD4⁺ T cells of migrated cells by percentages of T_reg cells in CD4⁺ T cells in original input PBMCs. Symbols indicate CI-T_reg of individual patients. Means are indicated.