Inhibition of T_reg cell–specific trafficking toward CSF supernatants with the use of anti-CCL17 and anti-CCL22 mAbs. CI-T_reg of CSF supernatants obtained from patients with LM (n = 6) and CM (n = 3). After preincubation for 30 minutes at 4°C with anti-CCL17 and anti-CCL22 mAbs (1 μg/mL), T_reg cell migration was tested by transwell migration assays. Symbols indicate CI-T_reg of individual patients. Medians are indicated.