Sustained activation of the Akt kinase promotes leukemic cell survival. Leukemic cell viability was determined 48 hours after nucleofection with pcDNA3 (Control), myr.Akt, or CA MEK2 mRNA by Annexin V/PI staining. ○ represents the response of individual patients. Mean values are indicated by ●. Error bars indicate standard deviation. A total of 9 experiments were performed.