MMSET knockdown or disruption affects adherent growth of KMS-11 cells. (A) 105 empty vector control or MMSET shRNA-transduced KMS-11 cells were plated in triplicate in tissue culture flasks (day 0). Nonadherent and adherent cells were counted on the indicated days and then pooled and replated. (B) T-KO or random integrant control KMS-11 clones were plated and analyzed as in panel A. Average cell counts (mean ± SD) are presented.