Increased megakaryocyte progenitor numbers in Pf4-Cre/FAK-floxed mice. (A) Colony assays for CFU-MK demonstrate a significant increase in the number of colonies from Pf4-Cre/FAK-floxed mice compared with controls. The results shown are the mean (±SEM) of 3 independent experiments. ***P < .01. (B) Colony assays for CFU-G/M, BFU-E, and CFU-E from Pf4-Cre/FAK-floxed and WT mice. No significant differences were found between the groups. The results represent the mean (± SEM) of 3 independent experiments.